Spironolactone
- May support feminizing therapy goals
- Reduces androgenic (testosterone-related) effects
- Helps lower blood pressure and fluid retention
Product Information
Better health begins with the right choices.
Dr. J. Vázquez
General Medicine Doctor | REG: 282889782
Dr. Josefina Vázquez is an experienced physician with over three years in emergency medicine, reanimation, and specialized transport.
Description
Spironolactone is a potassium-sparing diuretic used to treat conditions such as high blood pressure, fluid retention, and certain hormone-sensitive disorders. It functions by blocking aldosterone, a hormone that promotes sodium and water retention, which helps reduce fluid buildup and lower blood pressure.
In addition to its cardiovascular uses, spironolactone may be included in feminizing hormone therapy, often for transgender women and non-binary individuals. It acts as an anti-androgen, potentially reducing the effects of testosterone on the skin, hair, and body over time. Reported effects may include decreased facial/body hair, less scalp hair thinning, and softer skin, although changes can vary significantly by individual.
Spironolactone is usually taken orally once or twice per day. Dosage is personalized based on medical condition, lab results, and treatment goals. It is often combined with estrogen therapy in gender-affirming care. Monitoring of kidney function and electrolytes is recommended throughout treatment.
Side effects may include frequent urination, dizziness, breast tenderness, and elevated potassium levels. Spironolactone is not recommended for individuals with severe kidney impairment, high potassium, or Addison’s disease.
General Information
A potassium-sparing diuretic that helps remove excess fluid and lower blood pressure. It also functions as an anti-androgen in some treatment contexts.
It’s used to manage high blood pressure, heart failure, fluid retention, and as part of feminizing hormone therapy to help reduce the effects of testosterone.
It blocks aldosterone to reduce fluid retention and inhibits androgen receptors, decreasing testosterone’s effect on skin, hair, and sebaceous glands.
Doses vary by condition. For feminizing therapy, it often ranges from 50 to 200 mg daily, split into one or two doses. Your provider will tailor your dose to your lab results and goals.
Blood pressure effects may occur within days. Feminizing effects, where applicable, may develop gradually over several months and differ from person to person.
Take it when you remember. If it’s close to your next scheduled dose, skip the missed one. Do not double up doses.
Safety & Side Effects
Possible effects include:
- Increased urination
- Dizziness or lightheadedness
- Changes in potassium levels
- Breast tenderness or fatigue
Report side effects to your healthcare provider promptly.
Spironolactone is not recommended for people with:Severe kidney dysfunction, Addison’s disease, High potassium levels.
Yes, but drug interactions may occur. Inform your provider if you’re taking: ACE inhibitors, Potassium supplements or salt substitutes, Other diuretics or blood pressure medications
Not recommended during pregnancy or breastfeeding due to potential hormonal effects on the fetus or infant. Talk to your healthcare provider about your reproductive plans.
Alcohol may increase the risk of dizziness or dehydration. Discuss alcohol use with your healthcare provider.
Usage & Administration
Orally, once or twice daily, with a full glass of water.
At room temperature, away from heat, moisture, and direct sunlight. Keep out of reach of children.
It can be taken with or without food. If you experience nausea, taking it with food may help.
Some forms may be crushable. Ask your pharmacist before altering the form of any tablet.
Ordering & Delivery
To get Spironolactone, fill out a medical form or book a video consult. After approval, your prescription is sent to the pharmacy for fast delivery.
Spironolactone requires a valid prescription, which is issued after an online health assessment or video consultation.
Spironolactone is usually delivered in 1–2 business days after the prescription is received by the pharmacy.
Due to legal pharmacy rules, Spironolactone cannot be returned once dispensed. Be sure before confirming your order.
