Sandrena
Please select your gender (you can only order for yourself).
RequiredPrescription and health questionnaire required
Your treatment starts with completing our digital health questionnaire. If you already have a prescription, you can upload it during this process.
In some cases, the doctor may also request recent blood test results or an ID check to ensure the treatment is safe and suitable for you.
Your health, our priority
Transgender treatments always begin with a private video consultation with a doctor specialised in transgender care. These medicines can have a profound impact on your body, so the consultation ensures the treatment is right and safe for you.
During this process you will be treated with respect, understanding, and confidentiality, so you feel supported every step of the way.
Book Video Consultation- Relief for menopause symptoms
- Transdermal estrogen gel treatment
- Helps prevent early osteoporosis
Product Information
Better health begins with the right choices.
Dr. C. Muñoz Parada
General Medicine Doctor | REG: 30/4626091
Claudia Muñoz Parada is a licensed family medicine physician, specializing in primary care, pediatrics, and aesthetic medicine.
Description
Sandrena is a transdermal gel that contains estradiol hemihydrate, a form of estrogen. It treats symptoms associated with estrogen deficiency during natural or surgical menopause, such as hot flashes, night sweats, and vaginal dryness. Sandrena can also be used in the early prevention of postmenopausal osteoporosis.
The medication works by delivering estradiol directly through the skin into the bloodstream, bypassing the liver and reducing hormone fluctuations compared to oral estrogens. Estradiol binds to estrogen receptors, exerting anti-osteoporotic, lipid-regulating, and vasomotor-stabilizing effects. It also maintains the health of the skin, urinary tract, and bones.
In the body, Sandrena effectively raises estradiol levels to restore hormonal balance, improving symptoms of menopause while maintaining a favorable estradiol-to-estrone ratio. It offers stable blood levels with minimal daily fluctuations and can be easily adjusted based on individual therapeutic needs.
Sandrena is generally well-tolerated, though it requires combination with a progestogen in women with an intact uterus to prevent endometrial hyperplasia.
General Information
Sandrena is a hormone replacement therapy gel containing estradiol, used to treat estrogen deficiency symptoms.
It treats menopausal symptoms and helps prevent postmenopausal osteoporosis.
Estradiol is absorbed through the skin into the bloodstream, restoring natural hormone levels and improving menopausal symptoms.
The usual starting dose is 1.0 mg (1.0 g of gel) daily, adjusted based on clinical response.
Most users experience symptom relief within a few weeks, with maximum effects after 2–3 cycles.
Apply the missed dose as soon as possible unless more than 12 hours have passed. Otherwise, skip the missed dose and continue as scheduled.
Safety & Side Effects
Breast tenderness, skin irritation, bloating, or rare clotting events. Consult your doctor if symptoms persist or worsen.
Known or suspected breast cancer, estrogen-dependent tumors, unexplained vaginal bleeding, history of thromboembolism, or severe liver disease.
Caution is needed with drugs that induce or inhibit liver enzymes (like rifampicin or ketoconazole), which can affect estradiol levels.
No. Sandrena must not be used during pregnancy or breastfeeding.
Moderate alcohol intake is generally acceptable unless otherwise advised.
Usage & Administration
Apply the gel thinly to clean, dry skin on the lower trunk or thighs. Rotate application sites.
Store below 25°C. Protect from freezing and heat.
Food does not affect the application or absorption of the gel.
Ordering & Delivery
To get [Product name], fill out a medical form or book a video consult with a doctor via Transtoyou. After approval, your prescription is sent to the pharmacy for fast delivery.
[Product name] requires a valid prescription, which is issued after the doctor reviewed your answered in the medical questionnaire or via a video consultation with the doctor.
After approval by a doctor from Transtoyou, the prescription of [Product name] is forwarded to an affiliated pharmacy and typically shipped within 1–2 working days.
For safety and legal reasons prescription medication (RX) and in this case [Product name] is non-returnable once shipped.
