Nebivolol
Informational leaflet with dosage instructions and safety information.
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Nebivolol
- Nebivolol: Beta blocker used to treat high blood pressure and support heart function.
- Used for: Treatment of high blood pressure (hypertension) and, in some cases, chronic heart failure.
- Active ingredient: Nebivolol
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Product Information
Better health begins with the right choices.
Medically Verified
Dr. Georgi Varbanov
General Medicine Doctor | UIN: 0400005105Dr. Georgi Varbanov is a family medicine physician dedicated to evidence-based care and disease prevention.
What is Nebivolol?
Nebivolol is a prescription medicine that belongs to a group of medicines called beta blockers. It is mainly used to treat high blood pressure (hypertension) and may also be prescribed for certain patients with chronic heart failure.
Beta blockers work by affecting how your heart responds to stress hormones such as adrenaline. By slowing your heart rate and relaxing blood vessels, Nebivolol helps reduce strain on your heart.
High blood pressure often has no noticeable symptoms, but over time it increases your risk of serious health problems such as heart attack, stroke and kidney damage. Nebivolol helps lower blood pressure and reduce these long-term risks.
What is it used for?
Nebivolol is used to treat:
- High blood pressure (hypertension)
- Chronic heart failure (in selected patients, usually older adults)
High blood pressure
High blood pressure means that the force of blood pushing against your artery walls is consistently too high. If left untreated, this can damage blood vessels and organs.
Chronic heart failure
Heart failure does not mean your heart has stopped working. It means your heart is not pumping blood as effectively as it should. Nebivolol can help improve heart function and reduce symptoms such as shortness of breath and fatigue.
Nebivolol is often used alone or together with other blood pressure medicines.
How does the product work?
Nebivolol works by blocking beta-1 receptors in your heart. These receptors normally respond to adrenaline and increase your heart rate and blood pressure.
By blocking these receptors, Nebivolol:
- Slows down your heart rate
- Reduces the force of heart contractions
- Lowers blood pressure
- Decreases strain on the heart
Nebivolol also has a unique additional effect compared to some older beta blockers. It helps stimulate the release of nitric oxide, a natural substance that relaxes blood vessels. This improves blood flow and contributes to blood pressure reduction.
Because of this dual action, Nebivolol is sometimes considered more selective and better tolerated than traditional beta blockers.
Who should not use the product?
You should not use Nebivolol if:
- You are allergic to nebivolol
- You have severe liver impairment
- You have very slow heart rate (bradycardia)
- You have certain heart rhythm disorders
- You have untreated heart failure that is unstable
- You have very low blood pressure
- You have severe circulation problems
Nebivolol may not be suitable if you have asthma or certain lung diseases, as beta blockers can sometimes worsen breathing symptoms.
Always inform your doctor about your full medical history before starting treatment.
Pregnancy and breastfeeding
If you are pregnant or planning to become pregnant, speak to a doctor before using Nebivolol. Beta blockers can affect blood flow to the placenta and may influence the baby’s growth.
Nebivolol may pass into breast milk. You should consult a doctor before breastfeeding while using this medication.
How to use and dosage
Always take Nebivolol exactly as prescribed.
For high blood pressure, the usual starting dose is:
- 5 mg once daily (dose may vary depending on your situation)
For chronic heart failure, treatment is usually started at a lower dose and gradually increased under medical supervision.
Take the tablet:
- Once daily
- At the same time each day
- With or without food
- Swallow with water
Do not stop taking Nebivolol suddenly, as this can worsen heart symptoms. If treatment needs to be stopped, your doctor will gradually reduce the dose.
Possible side effects
Like all medicines, Nebivolol may cause side effects, although not everyone experiences them.
Common side effects include:
- Headache
- Dizziness
- Fatigue
- Slow heart rate
- Nausea
- Shortness of breath
Less common but more serious side effects may include:
- Severe slowing of heart rate
- Low blood pressure
- Worsening heart failure
- Allergic reactions
Because Nebivolol slows the heart rate, you may feel tired or lightheaded when starting treatment. These symptoms often improve as your body adjusts.
Seek medical attention if you experience fainting, severe dizziness, swelling of the legs, or worsening breathing problems.
Important safety information
Before starting Nebivolol, tell your doctor if you:
- Have asthma or chronic lung disease
- Have diabetes (beta blockers can mask symptoms of low blood sugar)
- Have thyroid problems
- Have circulation problems
- Have kidney or liver disease
- Have a history of depression
If you have diabetes, Nebivolol may hide warning signs of low blood sugar, such as a fast heartbeat. Regular monitoring may be required.
Nebivolol can interact with other heart medicines, calcium channel blockers, antiarrhythmic drugs and certain antidepressants.
Regular blood pressure checks are important while taking this medication.
When to seek medical help
Seek urgent medical attention if you experience:
- Severe dizziness or fainting
- Chest pain
- Extremely slow heartbeat
- Severe shortness of breath
- Signs of an allergic reaction (swelling of face, lips or throat)
Contact your doctor if:
- Your symptoms worsen
- You develop new swelling in your legs
- You feel persistent fatigue
- Your blood pressure remains uncontrolled
If you are unsure whether your symptoms are related to your blood pressure treatment, you can book a secure video consultation with a licensed doctor via Transtoyou for personalised advice. If symptoms are severe or sudden, seek urgent medical care immediately.
General Information
What is [Product name] used for?
Nebivolol is a beta blocker used to treat high blood pressure (hypertension). In some patients with stable chronic heart failure, it is also prescribed to support heart function.
Lowering blood pressure reduces the long-term risk of heart attack, stroke and kidney damage.
How does [Product name] lower blood pressure?
Nebivolol blocks beta-1 receptors in the heart, slowing the heart rate and reducing the force of contraction. This lowers blood pressure.
It also increases nitric oxide release, which relaxes blood vessels and improves blood flow. This dual effect makes it more selective than many older beta blockers.
How does [Product name] work in the body?
Nebivolol starts lowering blood pressure within a few hours.
Full blood pressure control usually develops within 1 to 2 weeks.
Maximum effect may take several weeks.
You should continue taking it daily, even if you feel well.
What is the general recommended dosage for [Product name]?
For high blood pressure, the usual dose is 5 mg once daily.
Some patients may start on a lower dose, especially older adults or those with kidney problems.
For chronic heart failure, treatment begins at a low dose and is gradually increased under medical supervision.
Is [Product name] better than Bisoprolol or Metoprolol?
Nebivolol, bisoprolol and metoprolol are all beta blockers used to treat high blood pressure and heart conditions.
Nebivolol is more beta-1 selective and has additional vasodilating properties through nitric oxide release. Some patients experience fewer side effects such as fatigue or sexual dysfunction, but individual response varies.
The best choice depends on your medical history and cardiovascular profile.
Can I exercise while taking [Product name]?
Yes, in most cases regular physical activity is encouraged.
However, because Nebivolol lowers heart rate, your maximum heart rate during exercise may be lower than usual. If you experience dizziness or shortness of breath, reduce intensity and seek medical advice.
Safety & Side Effects
Does [Product name] slow your heart rate?
Yes. Nebivolol reduces heart rate as part of its therapeutic effect.
A slightly lower resting pulse is expected. However, if your heart rate becomes very slow or you experience dizziness or fainting, medical review is required.
Why does [Product name] make me tired?
Fatigue is a common side effect when starting beta blocker treatment.
Because Nebivolol slows heart rate and reduces adrenaline activity, some people feel more tired initially. This usually improves within a few weeks.
Persistent or severe fatigue should be discussed with a doctor.
Does [Product name] cause weight gain?
Nebivolol is not commonly associated with significant weight gain.
However, fluid retention may occur in patients with heart failure. New or worsening swelling of the legs should be assessed promptly.
Does [Product name] cause erectile dysfunction?
Beta blockers can sometimes affect sexual function. However, Nebivolol may have a lower risk of erectile dysfunction compared to older beta blockers due to its nitric oxide–mediated blood vessel relaxation.
If sexual side effects occur, medical advice should be sought.
Is [Product name] safe for people with asthma?
Nebivolol is more selective for heart receptors than older beta blockers. However, caution is still required in patients with asthma or chronic lung disease.
Always inform your doctor if you have breathing problems before starting treatment.
Can [Product name] affect blood sugar?
Yes. Nebivolol can mask symptoms of low blood sugar, such as a fast heartbeat.
If you have diabetes, regular glucose monitoring is important.
Is it safe to drink alcohol while using [Product name]?
Alcohol can increase dizziness and may enhance the blood pressure-lowering effect.
Moderate alcohol intake may be acceptable for some patients, but caution is advised, especially when starting treatment.
Usage & Administration
What is the best time to take [Product name]?
Nebivolol can be taken the best in the morning or evening. The most important factor is taking it at the same time every day.
It can be taken with or without food.
Can [Product name] be stopped suddently?
No. Nebivolol should not be stopped abruptly.
Sudden discontinuation can cause a rebound increase in blood pressure or worsen heart symptoms. Dose reduction should always be gradual under medical supervision.
What should I do if I forget a dose?
If you remember on the same day, take the missed dose as soon as possible.
If it is close to your next dose, skip the missed dose. Do not take a double dose.
Is [Product name] safe for long-term use?
Yes. Nebivolol is commonly prescribed as a long-term treatment for blood pressure and heart conditions.
Regular monitoring of blood pressure and heart rate is recommended.
Ordering & Delivery
How can I order [Product name] online?
Do I need a prescription for [Product name]?
[Product name] requires a valid prescription, which is issued after the doctor reviewed your answered in the medical questionnaire or via a video consultation with the doctor.
How fast is [Product name] delivered?
After approval by a doctor from Transtoyou, the prescription of [Product name] is forwarded to an affiliated pharmacy and typically shipped within 1–2 working days.
Can I return [Product name] if I change my mind?
For safety and legal reasons prescription medication (RX) and in this case [Product name] is non-returnable once shipped.
What Nebivolol is and what it is used for?
Nebivolol contains the active substance nebivolol, a selective beta-1 receptor blocker that acts on the cardiovascular system.
Nebivolol is used:
- To treat essential (primary) high blood pressure
- To treat stable mild to moderate chronic heart failure in patients aged 70 years and older, in addition to standard therapy
Nebivolol lowers blood pressure by slowing the heart rate, reducing the force of heart contractions and relaxing blood vessels. In heart failure, it helps support heart function when used alongside other treatments.
What you need to know before taking Nebivolol?
Do not take Nebivolol if:
- You are allergic to nebivolol or any of the other ingredients
- You have very low blood pressure
- You have severe circulation problems in your arms or legs
- Your resting heart rate is very slow (below 60 beats per minute)
- You have certain serious heart rhythm disorders such as second or third degree AV block or sick sinus syndrome
- You have acute or worsening heart failure requiring intravenous treatment
- You have cardiogenic shock
- You have asthma, bronchospasm or severe breathing problems
- You have untreated pheochromocytoma
- You have severe liver impairment
- You have metabolic acidosis such as diabetic ketoacidosis
Talk to your doctor before taking Nebivolol if you have slow heart rate, coronary artery spasm (Prinzmetal angina), untreated chronic heart failure, first degree AV block, circulation problems such as Raynaud’s syndrome, diabetes, thyroid disorders, chronic lung disease, psoriasis or severe kidney impairment.
Nebivolol may mask symptoms of low blood sugar and signs of an overactive thyroid.
Tell your doctor if you are taking other medicines, especially medicines for heart rhythm disorders, high blood pressure, depression, asthma, diabetes or medicines used during anaesthesia.
Nebivolol is not recommended in children and adolescents under 18 years.
Nebivolol contains lactose.
How to take Nebivolol?
Always take Nebivolol exactly as prescribed.
For high blood pressure, the usual dose is 5 mg once daily. In elderly patients or those with kidney impairment, treatment may start with 2.5 mg once daily.
Blood pressure reduction usually becomes noticeable within 1 to 2 weeks. The full effect may take up to 4 weeks.
For chronic heart failure, treatment is started at a low dose, usually 1.25 mg once daily, and gradually increased every 1 to 2 weeks under medical supervision. The maximum recommended dose is 10 mg once daily.
The tablet should be taken once daily, preferably at the same time each day, with water. It can be taken with or without food.
Do not stop taking Nebivolol suddenly. Treatment should be reduced gradually under medical supervision.
If you take more than prescribed, symptoms may include very slow heart rate, low blood pressure, fainting, breathing difficulties or worsening heart failure. Seek medical attention immediately.
If you forget a dose, take it as soon as you remember on the same day. Do not take a double dose.
Possible side effects of Nebivolol
Like all medicines, Nebivolol can cause side effects, although not everybody gets them.
When used for high blood pressure, common side effects include:
- Headache
- Dizziness
- Fatigue
- Tingling sensation
- Diarrhoea or constipation
- Nausea
- Shortness of breath
- Swelling of the legs or ankles
Uncommon side effects include slow heart rate, low blood pressure, depression, sleep disturbances, erectile dysfunction, bronchospasm and skin reactions.
Very rare side effects include fainting and worsening of psoriasis.
In heart failure patients, very common side effects include slow heart rate and dizziness. Worsening heart failure, low blood pressure and swelling of the lower limbs have also been reported.
Severe allergic reactions, including swelling of the face, lips or tongue, may occur rarely and require immediate medical attention.
How to store Nebivolol
- Keep this medicine out of the sight and reach of children
- Do not use this medicine after the expiry date stated on the packaging
- Store below 30°C
- Do not dispose of medicines via wastewater or household waste. Ask your pharmacist how to dispose of medicines you no longer use
This is a summary of the official patient leaflet. It does not replace the full package leaflet. Always read the official leaflet provided with your medication.
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