



Hydroxyzine
- Fast-acting antihistamine that reduces allergy symptoms
- Dual benefit of alleviating both allergic reactions and mild anxiety
- Simple oral formulation suitable for daily use with minimal side effects
Product Information
Better health begins with the right choices.
Dr. M. Sharoyko
Internal Medicine Physician | MNr. 80134
Dr. Marina Sharoyko is a medical specialist in clinical pharmacology and internal medicine, with additional expertise in cardiology and physiology.
Description
Hydroxyzine is a prescription antihistamine used to relieve allergic conditions such as itching, hives, rashes, and allergic rhinitis . It belongs to the first-generation antihistamines and works by blocking the action of histamine, a chemical released by the immune system during allergic reactions.
By doing so, hydroxyzine helps effectively reduce symptoms of allergic skin conditions ( allergy symptoms caused by hay fever, dust mites, or other environmental triggers).
Unlike some newer antihistamines, hydroxyzine also has a sedative and anxiolytic (anti-anxiety) effect . This makes it especially suitable for individuals who suffer from intense itching or have trouble sleeping due to their allergy symptoms. The effects usually begin within 15 to 60 minutes (within an hour) and last for 4 to 6 hours or longer, depending on the dose and individual response ( several hours, making it appropriate for both short-term relief and the treatment of persistent symptoms).
Hydroxyzine is commonly prescribed for chronic urticaria (hives), atopic dermatitis, allergic skin reactions, and sometimes as an adjunct treatment for anxiety or insomnia ( seasonal or chronic allergies, hives (urticaria), itchy eczema, or allergic skin reactions). The tablets are typically taken once or several times a day, depending on the severity of the symptoms and the physician’s instructions (body’s response). As with many first-generation antihistamines, drowsiness can occur. For that reason, hydroxyzine is often taken in the evening or at times when staying alert is not required.
As with all medications, hydroxyzine should be used under medical supervision, especially in individuals with liver or kidney impairment, the elderly, or those taking other central nervous system depressants.
General Information
Hydroxyzine is an oral antihistamine that provides relief from allergy symptoms and helps reduce anxiety by blocking H1 receptors.
Hydroxyzine is used to treat allergies such as itching, hives, and a runny nose. It is also used to manage mild anxiety and tension. Additionally, it can help with sedation, nausea and vomiting, and insomnia.
Hydroxyzine works by antagonizing H1 receptors, thereby blocking the effects of histamine and alleviating both allergic reactions and anxiety.
It also has a sedative and anxiolytic effect, as it influences the central nervous system (CNS) by enhancing GABA (a calming neurotransmitter) and reducing activity in certain brain areas, leading to relaxation, drowsiness, and reduced anxiety.
Additionally, it has an anti-nausea effect, acting on the chemoreceptor trigger zone (CTZ) in the brain, which helps control nausea and vomiting.
The dosage varies based on the condition; typically, it is taken once daily for allergies.
Hydroxyzine works relatively quickly. Tablets, capsules, and syrup start working within 15 to 60 minutes. Peak effects occur around 2 hours after administration. The duration is 4 to 6 hours, but sedation may last longer. Most patients notice relief within 30 minutes to an hour after ingestion.
Take the missed dose as soon as you remember, unless it is near your next scheduled dose;
Safety & Side Effects
Common side effects include drowsiness, dry mouth, and mild gastrointestinal discomfort.
Though rare, some individuals may be allergic to Hydroxyzine; discontinue use and seek medical help if you experience rash or difficulty breathing.
Due to its sedative effects, it may cause drowsiness that can affect alertness.
It may interact with sedatives and alcohol; always inform your doctor about all medications you are taking.
Only use it during pregnancy or breastfeeding if clearly needed and prescribed by your doctor.
However, long-term use of hydroxyzine may lead to increased tolerance, reduced effectiveness, and a risk of dependence (especially for anxiety or sleep use), along with cognitive and memory effects.
Chronic use of antihistamines, particularly in older adults, has been associated with memory issues and an increased risk of dementia. Other potential side effects over time include dry mouth, dizziness, constipation, urinary retention, and drowsiness.
Usage & Administration
Take it orally, with or without food, as directed by your healthcare provider.
Store in a cool, dry place away from direct sunlight.
Exceeding the prescribed dose may lead to increased drowsiness and other side effects; consult your doctor if an overdose is suspected.
Individuals with known hypersensitivity to Hydroxyzine or related compounds should avoid its use.
It can be taken with or without food; taking it with food may reduce gastrointestinal discomfort.
Do not alter the tablet form unless advised by your doctor.
Ordering & Delivery
To get Hydroxyzine, fill out a medical form or book a video consult. After approval, your prescription is sent to the pharmacy for fast delivery.
A prescription is mandatory for Hydroxyzine, which is handled through a short medical intake or doctor call.
After approval by a doctor, the prescription for Hydroxyzine is forwarded to the pharmacy and typically shipped within 1–2 working days.
Due to legal pharmacy rules, Hydroxyzine cannot be returned once dispensed. Be sure before confirming your order.
