Evorel

Evorel is a transdermal patch that releases estradiol into the bloodstream through the skin, providing continuous oestrogen replacement without daily tablets. 

It treats menopausal symptoms such as hot flushes, mood swings, and vaginal dryness, prevents osteoporosis, and supports transgender women in HRT regimes. 

The patch delivers a steady dose of estradiol that bypasses the digestive system and first-pass liver metabolism, producing smoother hormone levels and fewer ups and downs. 

Patches are usually applied twice weekly (changing every 3-4 days). The strength (25-100 µg/24 h) depends on symptom control and doctor recommendation. 

Some relief can appear within a week; maximum benefit is seen over 4-6 weeks. 

If a patch falls off, apply a new one and keep your normal change-over day. If you forget to replace it for more than 24 hours, you may experience spotting or return of symptoms. 

• Common: mild application-site irritation, headache, breast tenderness, bloating, and mood swings.
• Uncommon: high blood pressure, gallstones, migraine, weight change.
• Serious but rare: blood clots, stroke, heart attack, or breast/endometrial cancer with prolonged use. Any leg swelling, sudden chest pain, or jaundice warrants immediate attention.

Skin irritation at the application site is fairly common. Rarely, a true allergic rash may occur. If severe redness, swelling, or itching spreads beyond the patch, discontinue use and consult your doctor. 

Enzyme-inducing drugs (e.g., some epilepsy medicines) can lower estradiol levels. Always reveal your full medication list. 

It often improves sleep by reducing night sweats. 

No-remove the patch and contact your doctor if pregnancy occurs. 

Long-term HRT should be reviewed annually; lowest effective dose is advised. 

Alcohol does not directly interfere but can worsen hot flushes. 

Apply to clean, dry, hairless skin below the waist. Press firmly for 10 seconds to secure. Rotate sites to avoid irritation. Do not cut the patch-it will leak.

Keep in the sachet at room temperature away from direct heat. 

Avoid if you have or have had breast cancer, uterine cancer, unexplained vaginal bleeding, active blood clots, severe liver disease, or porphyria. It is not for use during pregnancy or breastfeeding. 

Using multiple patches may cause nausea and breast soreness. Remove extra patches and seek advice. 

To get [Product name], fill out a medical form or book a video consult with a doctor via Transtoyou. After approval, your prescription is sent to the pharmacy for fast delivery.

[Product name] requires a valid prescription, which is issued after the doctor reviewed your answered in the medical questionnaire or via a video consultation with the doctor.

After approval by a doctor from Transtoyou, the prescription of [Product name] is forwarded to an affiliated pharmacy and typically shipped within 1–2 working days.

For safety and legal reasons prescription medication (RX) and in this case [Product name] is non-returnable once shipped.