Evorel
Please select your gender (you can only order for yourself).
RequiredPrescription and health questionnaire required
Your treatment starts with completing our digital health questionnaire. If you already have a prescription, you can upload it during this process.
In some cases, the doctor may also request recent blood test results or an ID check to ensure the treatment is safe and suitable for you.
Your health, our priority
Transgender treatments always begin with a private video consultation with a doctor specialised in transgender care. These medicines can have a profound impact on your body, so the consultation ensures the treatment is right and safe for you.
During this process you will be treated with respect, understanding, and confidentiality, so you feel supported every step of the way.
Book Video ConsultationProduct Information
Better health begins with the right choices.
Dr. M. Sharoyko
Internal Medicine Physician | MNr. 80134
Dr. Marina Sharoyko is a medical specialist in clinical pharmacology and internal medicine, with additional expertise in cardiology and physiology.
Description
Evorel is a hormone patch that delivers a steady dose of estradiol, a bioidentical form of estrogen identical to that naturally produced by the body. It is used in hormone replacement therapy (HRT) to manage symptoms associated with reduced estrogen levels, such as those experienced during or after menopause. Evorel is also commonly used in estrogen and feminizing therapy, where it supports the development of female secondary sexual characteristics in individuals undergoing gender-affirming treatment.
The patch is applied directly to the skin, usually on the lower abdomen or buttocks, and replaced twice weekly. This transdermal delivery system allows estradiol to be absorbed steadily into the bloodstream, helping maintain stable hormone levels without the peaks and troughs that can occur with oral estrogen medications.
In menopausal care, Evorel helps alleviate symptoms such as hot flushes, mood changes, vaginal dryness, and sleep disturbances. It may also support the maintenance of bone density and overall well-being in individuals with estrogen deficiency.
For those using Evorel as part of feminizing hormone therapy, estradiol plays a key role in supporting physical changes such as breast development, softer skin, and fat redistribution. When combined with testosterone-suppressing medications, Evorel contributes to creating a hormonal environment that supports a more typically feminine physiology.
Dosing is individualized and may vary depending on the indication, symptom severity, and response to treatment. Patches come in multiple strengths to allow dose adjustments over time.
Possible side effects include skin irritation at the patch site, breast tenderness, mood changes, and mild bloating. As with all estrogen therapies, longer-term risks such as venous thromboembolism or cardiovascular complications should be assessed based on individual medical history and risk factors.
General Information
Evorel is a transdermal patch that releases estradiol into the bloodstream through the skin, providing continuous oestrogen replacement without daily tablets.
It treats menopausal symptoms such as hot flushes, mood swings, and vaginal dryness, prevents osteoporosis, and supports transgender women in HRT regimes.
The patch delivers a steady dose of estradiol that bypasses the digestive system and first-pass liver metabolism, producing smoother hormone levels and fewer ups and downs.
Patches are usually applied twice weekly (changing every 3-4 days). The strength (25-100 µg/24 h) depends on symptom control and doctor recommendation.
Some relief can appear within a week; maximum benefit is seen over 4-6 weeks.
If a patch falls off, apply a new one and keep your normal change-over day. If you forget to replace it for more than 24 hours, you may experience spotting or return of symptoms.
Safety & Side Effects
- Common: mild application-site irritation, headache, breast tenderness, bloating, and mood swings.
- Uncommon: high blood pressure, gallstones, migraine, weight change.
- Serious but rare: blood clots, stroke, heart attack, or breast/endometrial cancer with prolonged use. Any leg swelling, sudden chest pain, or jaundice warrants immediate attention.
Skin irritation at the application site is fairly common. Rarely, a true allergic rash may occur. If severe redness, swelling, or itching spreads beyond the patch, discontinue use and consult your doctor.
Enzyme-inducing drugs (e.g., some epilepsy medicines) can lower estradiol levels. Always reveal your full medication list.
It often improves sleep by reducing night sweats.
No-remove the patch and contact your doctor if pregnancy occurs.
Long-term HRT should be reviewed annually; lowest effective dose is advised.
Alcohol does not directly interfere but can worsen hot flushes.
Usage & Administration
Apply to clean, dry, hairless skin below the waist. Press firmly for 10 seconds to secure. Rotate sites to avoid irritation. Do not cut the patch-it will leak.
Keep in the sachet at room temperature away from direct heat.
Avoid if you have or have had breast cancer, uterine cancer, unexplained vaginal bleeding, active blood clots, severe liver disease, or porphyria. It is not for use during pregnancy or breastfeeding.
Using multiple patches may cause nausea and breast soreness. Remove extra patches and seek advice.
Ordering & Delivery
To get [Product name], fill out a medical form or book a video consult with a doctor via Transtoyou. After approval, your prescription is sent to the pharmacy for fast delivery.
[Product name] requires a valid prescription, which is issued after the doctor reviewed your answered in the medical questionnaire or via a video consultation with the doctor.
After approval by a doctor from Transtoyou, the prescription of [Product name] is forwarded to an affiliated pharmacy and typically shipped within 1–2 working days.
For safety and legal reasons prescription medication (RX) and in this case [Product name] is non-returnable once shipped.
