How fast is Estramon delivered?

After approval by a doctor from Transtoyou, the prescription of Estramon is forwarded to an affiliated pharmacy and typically shipped within 1–2 working days.

Can I return Estramon if I change my mind?

For safety and legal reasons prescription medication (RX) and in this case Estramon is non-returnable once shipped.

Estramon

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I am Male Not available for men

I am Female

I am Transgender

Prescription and health questionnaire required

Your treatment starts with completing our digital health questionnaire. If you already have a prescription, you can upload it during this process.

In some cases, the doctor may also request recent blood test results or an ID check to ensure the treatment is safe and suitable for you.

Your health, our priority

Transgender treatments always begin with a private video consultation with a doctor specialised in transgender care. These medicines can have a profound impact on your body, so the consultation ensures the treatment is right and safe for you.

During this process you will be treated with respect, understanding, and confidentiality, so you feel supported every step of the way.

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Twice-weekly estrogen patch
Used in menopause and feminizing therapy
Non-oral, consistent hormone delivery

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Prescription Included Issued by a licensed doctor and included in the price, no extra steps needed.
Private Video Consultation Speak directly with a specialist in a confidential and secure consultation.
100% Discreet & Private Packed and shipped without any indication of the contents.
Fast Delivery Dispatched within 24 - 48 hours from a certified pharmacy.

Product Information

Better health begins with the right choices.

Medically Verified

Dr. Marina Sharoyko

Internal Medicine Physician | MNr. 80134

Reviewed on: 17 May, 2025 View Profile

Dr. Marina Sharoyko is a medical specialist in clinical pharmacology and internal medicine, with additional expertise in cardiology and physiology.

Estramon® is a small, discreet transdermal patch that delivers 17-β-estradiol-the principal human estrogen-across the skin at a steady, physiologic rate.

Unlike tablets, the patch bypasses the digestive tract and first-pass liver metabolism, producing smoother hormone profiles and requiring substantially lower doses to achieve the same therapeutic effect. The silicone-based adhesive keeps the patch firmly in place during showering, swimming, and moderate exercise, yet allows easy removal without residue.

For women in the peri- or post-menopausal stage, Estramon rapidly relieves vasomotor hot flushes, night-sweats, palpitations, and the sleep disturbance that so often accompanies them. Long-term use improves vaginal lubrication, prevents accelerated loss of bone mineral density, and has been shown to normalise LDL and HDL cholesterol ratios, thereby supporting cardiovascular health. Because the dose is released continuously over three to four days, users report fewer hormone ‘peaks and troughs’ than with oral therapy and a lower incidence of mood swings or nausea.

Estramon has become an integral component of gender-affirming care for transgender women and non-binary individuals seeking physiologic estrogen levels.

Its non-oral route is especially valuable for patients with migraine, thrombophilia, or elevated triglycerides, in whom oral estrogens can exacerbate risk. Patch sizes from 25 µg to 100 µg per 24 hours enable precise titration based on serum estradiol and clinical goals such as breast development, skin softening, and fat redistribution.

Application is straightforward: after peeling away the protective liner, the patch is pressed onto clean, dry, hair-free skin of the lower abdomen or upper buttock and held for ten seconds. The site is rotated with each change to minimise local irritation. If a uterus is present, a progestogen-often oral micronised progesterone-is added for at least ten days per cycle to protect the endometrium.

When therapy is no longer needed, discontinuation is as simple as removing the patch; hormone levels fall to baseline within twenty-four hours.

General Information

What is [Product name]?

Estramon is a transdermal patch that delivers estradiol, a type of estrogen, through the skin for hormone replacement therapy or feminizing care.

What is [Product name] used for?

It is used to manage menopause symptoms and as part of feminizing hormone therapy in transgender women.

How does [Product name] work in the body?

The patch releases estradiol steadily into the bloodstream, helping to raise and maintain estrogen levels for symptom control or physical transition.

What is the general recommended dosage for [Product name]?

One patch is applied every three to four days, typically changed twice a week.

How long does it take to feel the effects of [Product name]?

Symptom relief may start within days to weeks. Feminizing changes develop gradually over months of consistent use.

What should I do if I forget a dose?

Apply a new patch as soon as possible and continue with your usual schedule. Do not use two patches at once.

Safety & Side Effects

What are the possible side effects of [Product name]?

Minor skin reactions are the most frequent complaints with Estramon: transient redness, faint itching, or a shiny outline after removal affect about one in five users and usually disappear within hours.

Rotating sites and applying the patch to clean, hair-free skin minimizes these issues. Systemic effects resemble those of any estradiol therapy. Temporary breast tenderness, mild water retention, and occasional headache are typical and improve after dose adjustment.

Less common are nausea, mood swings, or acne. In migraine sufferers, stepwise dose increases, and adequate hydration can prevent flare-ups. Serious events are rare but should be recognized early.

Estrogen slightly elevates the risk of blood clots, especially in smokers, individuals with obesity, or inherited clotting disorders; sudden leg pain, swelling, or shortness of breath warrants immediate medical help.

Because estradiol stimulates the endometrium, anyone with a uterus should also take a progesterone to prevent overgrowth and have any unexpected bleeding checked.

True allergy to estradiol itself is virtually unknown. Persistent rash or blistering under the patch is more likely a contact allergy to the acrylic or silicone adhesive; switching brands or changing to a gel solves most cases.

Anaphylaxis has not been reported, but generalised hives, facial swelling, or wheezing after application must be treated as a medical emergency.

What are the contraindications of [Product name]?

It should not be used if you have a history of breast cancer, unexplained vaginal bleeding, liver disease, or blood clots.

Can I combine [Product name] with other medications?

Yes, but always inform your healthcare provider about all medications you use, especially hormones or liver enzyme modulators.

Can I use this if I am pregnant or breastfeeding?

No. Estramon should not be used during pregnancy or while breastfeeding.

Is it safe to drink alcohol while using [Product name]?

Moderate alcohol use is not known to interfere, but excessive alcohol may affect hormone metabolism.

Usage & Administration

How do I administer [Product name]?

Apply the patch to clean, dry, hairless skin on the lower abdomen or buttocks. Rotate the site with each new patch.

How should I store [Product name] properly?

Store at room temperature in the original packaging away from heat and moisture.

Should I take [Product name] with food?

Not applicable. Estramon is a patch and not taken orally.

Can I crush or dissolve the tablet in water?

Not applicable. Estramon is a transdermal patch.

Ordering & Delivery

How can I order [Product name] online?

To get [Product name], fill out a medical form or book a video consult with a doctor via Transtoyou. After approval, your prescription is sent to the pharmacy for fast delivery.

Do I need a prescription for [Product name]?

[Product name] requires a valid prescription, which is issued after the doctor reviewed your answered in the medical questionnaire or via a video consultation with the doctor.

How fast is [Product name] delivered?

After approval by a doctor from Transtoyou, the prescription of [Product name] is forwarded to an affiliated pharmacy and typically shipped within 1–2 working days.

Can I return [Product name] if I change my mind?

For safety and legal reasons prescription medication (RX) and in this case [Product name] is non-returnable once shipped.

Product Documentation

All Variants

Select a variant to see specific documentation. Leaflets are provided for information purposes only. The official leaflet in the language of the country of delivery is supplied with the order.