Amitriptyline
- Low-dose bedtime tablet for pain, sleep & mood
- Improves nerve-pain tolerance within weeks
- Affordable, decades-long safety record
Product Information
Better health begins with the right choices.
Dr. M. Sharoyko
Internal Medicine Physician | MNr. 80134
Dr. Marina Sharoyko is a medical specialist in clinical pharmacology and internal medicine, with additional expertise in cardiology and physiology.
Description
Amitriptyline is used in low doses to help manage chronic pain conditions, including fibromyalgia. Fibromyalgia is a complex condition characterized by widespread musculoskeletal pain, fatigue, sleep disturbances, and increased sensitivity to pressure. Amitriptyline is not used to treat depression in this context, but rather to relieve physical symptoms and improve quality of life.
The way Amitriptyline works in fibromyalgia is linked to its ability to modulate pain signals in the nervous system. It affects the levels of certain neurotransmitters, including serotonin and norepinephrine, which play a role in how pain is perceived by the brain. This helps reduce the intensity of pain, improves sleep patterns, and may lessen fatigue or mood-related symptoms that often accompany fibromyalgia.
The medication is usually taken in low doses, often once daily in the evening or before bedtime. This schedule supports its sedative effects, which can help individuals with fibromyalgia who experience difficulty falling or staying asleep. Improvements in pain and sleep may take several days to a few weeks to become noticeable, and the dose may be adjusted based on response and tolerance.
Common side effects may include dry mouth, drowsiness, weight gain, or constipation. These effects are usually mild and may improve over time as the body adjusts. Because of its sedating properties, caution is advised when performing activities that require alertness, especially when starting the medication.
General Information
Amitriptyline is a tricyclic antidepressant that is commonly used in low doses to help manage chronic pain, including fibromyalgia. While originally developed to treat depression, its pain-modulating properties make it effective in non-psychiatric conditions as well.
In the context of fibromyalgia, Amitriptyline is used to relieve widespread musculoskeletal pain, improve sleep quality, and reduce associated symptoms such as fatigue. It is also sometimes used for other types of nerve pain or migraines.
Amitriptyline works by increasing the levels of certain neurotransmitters in the brain that help regulate pain signals and mood. This results in decreased pain sensitivity and improved sleep, which are both important in fibromyalgia management.
For fibromyalgia, the typical starting dose is 10 to 25 mg at bedtime. The dose may be adjusted gradually based on individual response and tolerance.
Some individuals may notice improvements in sleep and pain within a few days, but it often takes several weeks of consistent use to experience full benefits.
If you miss a dose, take it as soon as you remember, unless it is close to the time for your next dose. Do not double the dose to make up for the missed one.
Safety & Side Effects
Common side effects include dry mouth, drowsiness, dizziness, constipation, and weight gain. These are generally mild and may lessen over time.
Amitriptyline should not be used by individuals with certain heart conditions, recent myocardial infarction, or those taking monoamine oxidase inhibitors (MAOIs). A full medical review is important before starting the medication.
Some combinations may increase the risk of side effects or interactions. It is important to inform your prescriber about all other medications, including over-the-counter and supplements.
Use during pregnancy or breastfeeding should be discussed with a healthcare provider. It is generally used with caution and only if clearly needed.
Alcohol can increase the sedative effects of Amitriptyline and may intensify side effects like drowsiness or dizziness. Limiting or avoiding alcohol is recommended.
Usage & Administration
Swallow the tablet whole with water. It is usually taken once daily, preferably at bedtime.
Store at room temperature away from moisture and direct light. Keep the medication out of reach of children.
It can be taken with or without food. If you experience stomach discomfort, taking it with food may help.
It is recommended to swallow the tablet whole. Crushing or dissolving is not advised unless specifically instructed by your healthcare provider.
Ordering & Delivery
To get [Product name], fill out a medical form or book a video consult with a doctor via Transtoyou. After approval, your prescription is sent to the pharmacy for fast delivery.
[Product name] requires a valid prescription, which is issued after the doctor reviewed your answered in the medical questionnaire or via a video consultation with the doctor.
After approval by a doctor from Transtoyou, the prescription of [Product name] is forwarded to an affiliated pharmacy and typically shipped within 1–2 working days.
For safety and legal reasons prescription medication (RX) and in this case [Product name] is non-returnable once shipped.
